DESCRIPTION

AGS has published a new framework to assist clinicians to safely prescribe obesity medications in older adults.  Developed by the AGS Healthy Aging Special Interest Group and organized around a series of cases, the framework offers a practical approach to prescribing obesity medications, including GLP-1 medications, that act through gut-derived hormonal pathways to older adults. While these medications offer promising benefits for weight management, glycemic control, and other health conditions, older adults are under-represented in clinical trials. The AGS framework discusses key considerations for the use of obesity medications in older adults including how to apply the Geriatrics 5Ms Framework (Mind, Mobility, Medications, Multicomplexity, and Matters Most) to incretin therapy in older adults.